Acute Poisoning and Overdose: Clinical Management
Received: 01-Oct-2025 / Manuscript No. jabt-25-177834 / Editor assigned: 03-Oct-2025 / PreQC No. jabt-25-177834 / Reviewed: 17-Oct-2025 / QC No. jabt-25-177834 / Revised: 22-Oct-2025 / Manuscript No. jabt-25-177834 / Published Date: 29-Oct-2025 DOI: 10.4172/2155-9872.1000812
Abstract
This compilation examines critical aspects of toxicology and poisoning management, focusing on diverse substances and scenarios. It covers opioid and synthetic cannabinoid overdoses, acetaminophen toxicity, organophosphate poisoning, and heavy metal exposure. Key themes include emergency department interventions, diagnostic challenges, treatment protocols, and public health implications. Additionally, the collection addresses snakebite envenoming, alcohol intoxication, plant poisonings, carbon monoxide exposure, and medication errors, offering updated clinical guidance and preventive strategies to improve patient safety and outcomes across various toxicological emergencies.
Keywords: Opioid Overdose; Synthetic Cannabinoids; Acetaminophen Toxicity; Organophosphate Poisoning; Heavy Metal Poisoning; Snakebite Envenoming; Alcohol Intoxication; Carbon Monoxide Poisoning; Medication Errors; Emergency Management
Introduction
This article systematically reviews current approaches to managing opioid overdoses in emergency departments, highlighting effective interventions and areas for improvement in clinical practice. It synthesizes evidence to guide clinicians in optimizing patient outcomes through timely and appropriate care [1].
This review delves into the clinical presentation and toxicological analysis of poisonings involving synthetic cannabinoids. It discusses diagnostic challenges, treatment strategies, and the diverse range of adverse effects observed in patients exposed to these rapidly evolving substances [2].
This article provides essential updates on the clinical management of acetaminophen toxicity, covering recent advancements in risk assessment, novel antidote administration protocols, and strategies for managing complex cases, ensuring clinicians have the latest evidence-based guidance [3].
This review offers an overview of acute organophosphate poisoning, a significant global health issue. It details the pathophysiology, clinical manifestations, and the latest evidence-based strategies for critical care management, emphasizing prompt diagnosis and effective antidote therapy [4].
This review provides an updated look at the impact of heavy metals on human health, detailing mechanisms of toxicity, diagnostic approaches, and current challenges in managing heavy metal poisoning. It emphasizes the need for continued research and public health interventions [5].
This article discusses the global crisis of snakebite envenoming, highlighting the burden on public health systems, challenges in antivenom availability and distribution, and opportunities for improving prevention, diagnosis, and clinical management strategies, especially in affected regions [6].
This comprehensive review focuses on the emergency department management of alcohol and ethanol intoxication. It covers the clinical presentation, diagnostic workup, and evidence-based treatment protocols for both acute alcohol poisoning and withdrawal, emphasizing supportive care and complication prevention [7].
This review addresses the challenges of plant poisoning, particularly in pediatric populations. It discusses common toxic plants, their clinical effects, and current management strategies, emphasizing the importance of accurate plant identification and symptomatic supportive care in emergency settings [8].
This article provides an in-depth look at carbon monoxide poisoning, covering its insidious nature, diverse clinical manifestations, and critical diagnostic considerations. It details current management guidelines, including oxygen therapy and hyperbaric oxygen treatment, to mitigate long-term neurological sequelae [9].
This review investigates medication errors that result in overdose, analyzing contributing factors such as prescribing errors, dispensing errors, and patient non-adherence. It explores various preventive strategies and system-level interventions aimed at enhancing patient safety and reducing iatrogenic harm [10].
Description
This article systematically reviews current approaches to managing opioid overdoses in emergency departments, highlighting effective interventions and areas for improvement in clinical practice. It synthesizes evidence to guide clinicians in optimizing patient outcomes through timely and appropriate care [1]. This review delves into the clinical presentation and toxicological analysis of poisonings involving synthetic cannabinoids. It discusses diagnostic challenges, treatment strategies, and the diverse range of adverse effects observed in patients exposed to these rapidly evolving substances [2]. This article provides essential updates on the clinical management of acetaminophen toxicity, covering recent advancements in risk assessment, novel antidote administration protocols, and strategies for managing complex cases, ensuring clinicians have the latest evidence-based guidance [3]. This review offers an overview of acute organophosphate poisoning, a significant global health issue. It details the pathophysiology, clinical manifestations, and the latest evidence-based strategies for critical care management, emphasizing prompt diagnosis and effective antidote therapy [4]. This review provides an updated look at the impact of heavy metals on human health, detailing mechanisms of toxicity, diagnostic approaches, and current challenges in managing heavy metal poisoning. It emphasizes the need for continued research and public health interventions [5]. This article discusses the global crisis of snakebite envenoming, highlighting the burden on public health systems, challenges in antivenom availability and distribution, and opportunities for improving prevention, diagnosis, and clinical management strategies, especially in affected regions [6]. This comprehensive review focuses on the emergency department management of alcohol and ethanol intoxication. It covers the clinical presentation, diagnostic workup, and evidence-based treatment protocols for both acute alcohol poisoning and withdrawal, emphasizing supportive care and complication prevention [7]. This review addresses the challenges of plant poisoning, particularly in pediatric populations. It discusses common toxic plants, their clinical effects, and current management strategies, emphasizing the importance of accurate plant identification and symptomatic supportive care in emergency settings [8]. This article provides an in-depth look at carbon monoxide poisoning, covering its insidious nature, diverse clinical manifestations, and critical diagnostic considerations. It details current management guidelines, including oxygen therapy and hyperbaric oxygen treatment, to mitigate long-term neurological sequelae [9]. This review investigates medication errors that result in overdose, analyzing contributing factors such as prescribing errors, dispensing errors, and patient non-adherence. It explores various preventive strategies and system-level interventions aimed at enhancing patient safety and reducing iatrogenic harm [10].
Conclusion
This collection of articles and reviews provides a comprehensive overview of various acute toxicology and poisoning scenarios. Key topics include the systematic management of opioid overdoses in emergency departments, covering interventions and strategies for optimizing patient outcomes. It also addresses the clinical and toxicological aspects of synthetic cannabinoid poisonings, highlighting diagnostic challenges and treatment approaches for these evolving substances. Updates on acetaminophen toxicity management, including risk assessment and antidote protocols, are presented. The global health issues of acute organophosphate poisoning and snakebite envenoming are discussed, emphasizing critical care, antivenom availability, and public health interventions. Reviews further delve into heavy metal poisoning mechanisms and management, alcohol and ethanol intoxication in emergency settings, and plant poisoning challenges, especially in pediatric populations. Critical insights into carbon monoxide poisoning, its diagnosis, and treatment are provided. Finally, the analysis extends to medication errors leading to overdose, exploring contributing factors and preventive strategies to enhance patient safety and reduce iatrogenic harm.
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Citation: Nasser F (2025) Acute Poisoning and Overdose: Clinical Management. jabt 16: 812. DOI: 10.4172/2155-9872.1000812
Copyright: © 2025 Fatima Nasser This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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