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ISSN: 2475-7640

Journal of Clinical and Experimental Transplantation
Open Access

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Advanced Immune Strategies for Hematopoietic Stem Cell Transplantation

Chen Li*
Department of Transplant Medicine, Shanghai Medical University, China
*Corresponding Author : Chen Li, Department of Transplant Medicine, Shanghai Medical University, China, Email: c.li@shanghaitransplant.cn

Received Date: Mar 03, 2025 / Published Date: Mar 31, 2025

Abstract

This research compilation investigates cutting-edge immune modulation strategies in hematopoietic stem cell transplantation (HSCT). It covers advancements in preventing graft-versus-host disease (GvHD) and enhancing graft-versus-leukemia (GvL) effects. Topics include CAR-T cell therapy, mesenchymal stem cells, cytokine therapy, donor lymphocyte infusion, gene-modified T cells, gut microbiome manipulation, checkpoint inhibitors, induced pluripotent stem cells, and regulatory T cells. The goal is to refine HSCT protocols and develop novel therapeutics for better patient outcomes.

Keywords: Stem Cell Transplantation; Immune Modulation; Graft-versus-Host Disease; Graft-versus-Leukemia Effect; CAR-T Cells; Mesenchymal Stem Cells; Regulatory T Cells; Gut Microbiome; Cytokine Therapy; Checkpoint Inhibitors

Citation: Li C (2025) Advanced Immune Strategies for Hematopoietic Stem Cell Transplantation. J Clin Exp Transplant 10: 275.

Copyright: © 2025 Chen Li This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited

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