中国P站

Abstract

Biofilms significantly complicate chronic wounds, leading to delayed healing and increased antimicrobial resistance. These persistent infections present diagnostic difficulties and challenge conventional antibiotic therapies. Research highlights the critical impact of biofilms on host-pathogen interactions and wound management, emphasizing the need for novel therapeutic approaches. Recent advancements explore strategies beyond traditional antimicrobials, including antimicrobial peptides, bacteriophages, nanotechnology, and targeted biofilm disruption. The focus is on innovative diagnostic tools and diverse interventions to overcome biofilm resistance, modulate host responses, and enhance wound recovery effectively, promising improved clinical outcomes.