Antibody Engineering: Advancing Therapeutics for Disease
Received Date: Sep 01, 2025 / Accepted Date: Sep 29, 2025 / Published Date: Sep 29, 2025
Abstract
Antibody engineering is a critical field enhancing therapeutic antibodies for improved efficacy, specificity, and pharmacokinetics.
Key innovations include bispecific antibodies, antibody-drug conjugates (ADCs), and engineered antibody fragments. Fc region en
gineering modulates immune effector functions, while phage display and humanization techniques accelerate antibody development.
Immune checkpoint inhibitors have transformed cancer therapy. Protein engineering and computational approaches further refine
antibody design for stability and potency, driving the development of advanced immunotherapies.
Citation: O’Neill DK (2025) Antibody Engineering: Advancing Therapeutics for Disease. Immunol Curr Res 09: 279. Doi: 10.4172/icr.1000279
Copyright: © 2025 Dr. Kevin O’Neill This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permitsunrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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