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Abstract

The provided articles consistently explore the role of epigenetic mechanisms—including DNA methylation, histone modifications, and non-coding RNAs—in cardiovascular health, aging, and disease. They detail how these epigenetic alterations contribute to cardiac dysfunction, remodeling, and conditions like heart failure and myocardial infarction. The reviews and articles collectively highlight the impact of epigenetics on myocyte function, proliferation, and senescence, suggesting epigenetic modulation as a promising avenue for therapeutic interventions to combat age-related cardiac decline and promote regeneration.