中国P站

Abstract

Cellular homeostasis is vital for survival, maintained by complex, interconnected mechanisms. This involves precise regulation of iron levels, dynamic metabolic pathways, and adaptable mitochondrial dynamics. Organelle crosstalk, notably between the ER, mitochondria, and lysosomes, is fundamental for cellular balance. Protein quality control, through the ubiquitin proteasome system and autophagy, ensures cellular integrity. Tightly controlled cellular pH, alongside cell plasticity and epigenetic changes, are also essential. Disruptions in these processes significantly contribute to various diseases, including cancer, highlighting their critical roles in health.