Cellular Stress Responses: Adaptation, Disease, Therapeutics
Received Date: May 01, 2025 / Published Date: May 29, 2025
Abstract
Diverse cellular stress responses, including the Integrated Stress Response (ISR), ER stress, mitochondrial dysfunction responses, and the Heat Shock Response (HSR), are vital for maintaining homeostasis. Dysregulation in these pathways, alongside the DNA Damage Response (DDR), oxidative stress, and autophagy, underlies various pathologies from metabolic disorders and neurodegeneration to cancer. Key regulators like the ER-mitochondria axis and NRF2 pathway mediate cellular resilience. Understanding these interconnected responses and their disease implications offers promising avenues for novel therapeutic strategies.
Citation: Rossi DE (2025) Cellular Stress Responses: Adaptation, Disease, Therapeutics. cmb 71: 389.
Copyright: 漏 2025 Dr. Elena Rossi This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Select your language of interest to view the total content in your interested language
Share This Article
Recommended Journals
Open Access Journals
Article Usage
- Total views: 414
- [From(publication date): 0-0 - Apr 09, 2026]
- Breakdown by view type
- HTML page views: 335
- PDF downloads: 79
