Cerebrospinal Fluid Biomarkers For Neurological Disease Diagnosis
Received Date: Nov 03, 2025 / Published Date: Dec 01, 2025
Abstract
Cerebrospinal fluid (CSF) biomarkers are central to the diagnosis and management of neurological disorders, with ongoing re
search focused on novel protein and metabolite signatures to enhance diagnostic precision and prognostic accuracy. Studies are
exploring multi-analyte panels for bacterial meningitis, neurofilament light chain for neuroaxonal damage, and microRNAs for viral
encephalitis. Advances include RT-QuIC assays for prion diseases, proteomic and metabolomic profiling for infections and inflam
mation, and ultrasensitive viral antigen detection. Treatment response is also assessed via CSF biomarkers. These advancements are
critical for institutions like the Department of Clinical Research at Aarhus University.
Citation: 脗聽Olsen H (2025) Cerebrospinal Fluid Biomarkers For Neurological Disease Diagnosis. JNID 16: 595.
Copyright: 聽漏 2025 Henrik Olsen This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,聽distribution and reproduction in any medium, provided the original author and source are credited
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