Cervical Cancer Metastasis: Pathways, Microenvironment, and Therapy
Received Date: Dec 01, 2025 / Published Date: Dec 29, 2025
Abstract
This review synthesizes current knowledge on cervical cancer metastasis, detailing its intricate mechanisms from primary tumor to distant sites. It highlights the roles of epithelial-mesenchymal transition (EMT), the tumor microenvironment (TME), vascular invasion, pre-metastatic niche formation, and organotropism. Key molecular players, signaling pathways, and biomarkers are discussed. Therapeutic strategies, including anti-angiogenic agents, targeted therapies, and immunotherapies, are examined for their potential to inhibit metastasis and improve patient outcomes
Citation: Alvarez DM (2025) Cervical Cancer Metastasis: Pathways, Microenvironment, and Therapy. Current Trends Gynecol Oncol 10: 310.
Copyright: 漏 2025 Dr. Maya Alvarez This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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