Complement System: Immunity, Disease, And Therapeutics
Received Date: Jul 01, 2025 / Accepted Date: Jul 29, 2025 / Published Date: Jul 29, 2025
Abstract
The complement system is a vital component of innate immunity, involved in pathogen defense and immune complex clearance.
Its dysregulation is implicated in inflammatory and autoimmune diseases. This review explores key complement pathways, including
lectin, alternative, and terminal pathways, and their therapeutic implications. Anaphylatoxins, complement regulators, and cross-talk
with other immune systems are discussed. Emerging roles in neuroinflammation, cancer immunity, and as diagnostic markers are
highlighted, alongside therapeutic strategies targeting the complement cascade.
Citation: Novak DT (2025) Complement System: Immunity, Disease, And Therapeutics. Immunol Curr Res 09: 271. Doi: 10.4172/icr.1000271
Copyright: © 2025 Dr. Tomas Novak This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution and reproduction in any medium, provided the original author and source are credited.
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