COVID-19?s Neurological Complications: Mechanisms and Management
Received Date: Sep 03, 2025 / Published Date: Oct 01, 2025
Abstract
The COVID-19 pandemic has led to a diverse range of neurological complications, including headache, anosmia, stroke, en
cephalitis, and Guillain-Barré syndrome. Pathogenic mechanisms involve direct viral impact, neuroinflammation, immune dysregu
lation, and vascular effects. Cerebrovascular complications, severe CNS involvement, and peripheral nervous system disorders are
significant concerns. Long-term neurological sequelae and sleep disturbances are also recognized. The immune response and mi
crovascular dysfunction play key roles. Further research is crucial for understanding and managing these neurological manifestations.
Keywords: COVID-19脥戮 Neurological Complications脥戮 Stroke脥戮 Encephalitis脥戮Guillain-Barré Syndrome脥戮 Long COVID脥戮 Neuroinflammation脥戮Headache脥戮 Anosmia脥戮 Microvascular Dysfunction
Citation: Haddad DO (2025) COVID-19’s Neurological Complications: Mechanisms and Management. JNID 16: 591. Doi: 10.4172/2314-7326.1000591
Copyright: © 2025 Dr. Omar Haddad This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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