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Abstract

Cytokine storms, characterized by severe inflammation, are a critical concern in various diseases. This compilation of research
delves into the molecular and cellular underpinnings of these events, the role of specific cytokines, and the impact of factors like the
gut microbiome and trained immunity. It highlights therapeutic avenues including pathway inhibition, antibody treatments, and novel
approaches like extracellular vesicles. Emphasis is placed on precision medicine through genetic profiling and the development of
diagnostic biomarkers for early detection and prognosis, ultimately aiming to mitigate organ damage and improve patient outcomes.