Diabesity: Mechanisms, Interventions, Management
Received Date: Nov 01, 2025 / Published Date: Dec 01, 2025
Abstract
This collection of reviews explores the complex interplay between obesity and type 2 diabetes, often termed ’diabesity.’ It highlights key molecular mechanisms such as chronic inflammation, insulin resistance, gut microbiota alterations, adipose tissue dysfunction, hormonal imbalances, epigenetics, and mitochondrial dysfunction that drive the pathogenesis and progression of these conditions. The discussions also cover diverse management strategies, including lifestyle interventions, novel pharmacotherapies, and surgical treatments. Understanding these intricate connections is crucial for developing effective preventative and therapeutic approaches against ’diabesity’ and its associated cardiovascular complications.
Citation: Rinaldi M (2025) Diabesity: Mechanisms, Interventions, Management. jowt 15: 859.
Copyright: 漏 2025 Matteo Rinaldi This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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