Donor Liver Selection: Balancing Need, Risk, and Viability
Received Date: Jan 02, 2025 / Published Date: Jan 30, 2024
Abstract
Liver donor selection is a complex process balancing organ availability with patient need and recipient outcomes. Key considerations include donor age, medical history, comorbidities, and graft viability. Expanded Criteria Donors (ECDs) are increasingly utilized to address organ shortages, but careful evaluation is crucial to mitigate risks. Factors such as hepatic steatosis and ischemiareperfusion injury in DCD donors require specific management strategies. Advancements like machine perfusion are enhancing graft assessment and preservation, improving outcomes, particularly for ECDs and DCD grafts. Thorough evaluation, including psychosocial aspects and pre-existing conditions, is paramount for optimal donor selection and maximizing patient benefit.
Keywords: Liver Transplantation; Donor Selection; Expanded Criteria Donors; Organ Shortage; Graft Viability; Hepatic Steatosis; DCD Liver; Machine Perfusion; Donor Age; Viral Hepatitis
Citation: Alvarez S (2025) Donor Liver Selection: Balancing Need, Risk, and Viability. J Clin Exp Transplant 10: 272. Doi: 10.4172/2475-7640.1000272
Copyright: © 2025 Sofia Alvarez This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited
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