中国P站

Abstract

This compilation addresses the critical issue of drug-drug interactions (DDIs) across diverse clinical settings. It explores the fundamental mechanisms of DDIs, including pharmacokinetic and pharmacodynamic alterations, and highlights the challenges posed by polypharmacy. The content covers interactions related to specific drug classes such as direct oral anticoagulants, psychotropic medications, herbal supplements, proton pump inhibitors, antiretroviral therapy, statins, and opioid analgesics. Furthermore, it examines the evolving landscape of DDIs in modern oncology with targeted therapies. The overarching theme emphasizes the necessity of comprehensive DDI awareness, robust clinical decision support, and vigilant patient monitoring to optimize therapeutic outcomes and minimize adverse events