Endometrial Cancer: Molecular Pathways and Progression
Received Date: Aug 01, 2025 / Published Date: Aug 29, 2025
Abstract
Endometrial cancer pathogenesis is a complex interplay of hormonal, genetic, and epigenetic factors. Estrogen unopposed by progesterone is a key driver, alongside mutations and epigenetic alterations. Distinct molecular subtypes exist, influencing prognosis and treatment. The tumor microenvironment, inflammation, and genomic instability also play significant roles. Metabolic reprogramming and microRNA dysregulation are emerging areas of interest with therapeutic potential.
Citation: Roberts DL (2025) Endometrial Cancer: Molecular Pathways and Progression. Current Trends Gynecol Oncol 10: 292.
Copyright: 漏 2025 Dr. Leah Roberts This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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