Epigenetics: Gene Regulation, Disease, and Therapeutic Potential
*Corresponding Author:Received Date: Aug 01, 2025 / Accepted Date: Aug 29, 2025 / Published Date: Aug 29, 2025
Citation: Santos DM (2025) Epigenetics: Gene Regulation, Disease, and Therapeutic Potential. Int J Inflam Cancer Integr Ther 12: 357.DOI: 10.4172/2381-8727.1000357
Copyright: © 2025 Dr. Maria Santos This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Epigenetic regulation, through mechanisms like DNA methylation, histone modifications, and non-coding RNAs, is central to gene expression control, cellular differentiation, and response to stimuli. Dysregulation is implicated in cancer and inflammatory diseases, offering therapeutic targets. Aberrant methylation patterns are cancer hallmarks, while specific histone marks indicate gene activity. Environmental factors can induce epigenetic changes. Epigenetic biomarkers are crucial for personalized medicine in cancer diagnosis and treatment. Epigenetic drugs (’epidrugs’) and targeting epigenetic pathways represent promising therapeutic strategies for various diseases, including those affecting immune function and inflammation.
