Fibromyalgia Research: Pathophysiology, Therapies, and Future Directions
Received Date: Jun 02, 2025 / Published Date: Jun 30, 2025
Abstract
Fibromyalgia research is rapidly advancing our understanding of its complex pathophysiology, including central sensitization, neuroinflammation, and genetic predispositions. Emerging therapeutic strategies involve personalized medicine, neuromodulation, and the gut microbiome, emphasizing a multidisciplinary approach. Genetic studies aim to identify risk factors and guide treatment. Neuromodulation techniques and gut microbiome interventions show promise. Research also focuses on neuroinflammation, sleep disturbances, and the biopsychosocial model. Novel pharmacological agents are being developed for improved efficacy and safety.
Keywords: Fibromyalgia; Central Sensitization; Neuroinflammation; Gut Microbiome; Personalized Medicine; Neuromodulation; Genetic Predispositions; Sleep Disturbances; Biopsychosocial Model; Pharmacological Treatments
Citation: Johansson E (2025) Fibromyalgia Research: Pathophysiology, Therapies, and Future Directions. J Pain Relief 14: 746 Doi: 10.4172/2167-0846.1000746
Copyright: © 2025 Erik Johansson This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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