Greener Pharmaceutical Synthesis: Catalysis and Flow
Received Date: Jul 02, 2025 / Published Date: Jul 30, 2025
Abstract
This research compilation showcases innovative strategies in pharmaceutical synthesis, emphasizing sustainability, efficiency, and safety. Key areas include green chemistry for scalable intermediate synthesis, continuous flow processing for complex molecules and hazardous reactions, and biocatalysis for chiral amine production. Advancements in catalysis, including C-H functionalization, oxidation using earth-abundant metals, and heterogeneous catalysts, are presented. Process control through PAT in crystallization and effective polymorph screening ensure API quality. Solvent recycling initiatives further contribute to environmentally responsible manufacturing. These developments collectively aim to optimize pharmaceutical production
Keywords: Green Chemistry; Continuous Flow Synthesis; Biocatalysis; Catalysis; Process Intensification; Polymorph Control; Pharmaceutical Manufacturing; Sustainable Synthesis; Crystallization; C-H Functionalization
Citation: Ramirez DS (2025) Greener Pharmaceutical Synthesis: Catalysis and Flow. J Mol Pharm Org Process Res 13: 296. Doi: 10.4172/2329-9053.1000296
Copyright: © 2025 Dr. Sofia Ramirez This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited
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