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Abstract

This collection of research investigates the multifaceted signaling networks governing immune cell behavior, essential for
immunity and disease. It details how pathways regulate T cell activation, macrophage polarization, neutrophil recruitment, and B cell
responses. The studies also explore the interplay between innate and adaptive immunity, the impact of metabolic reprogramming and
non-coding RNAs, signaling, and the dysregulation of these networks in autoimmune diseases. The findings underscore the critical
importance of these signaling mechanisms for immune homeostasis and highlight potential targets for novel immunotherapies.