Immunometabolism: Fueling Immune Cell Function And Health
Received Date: May 01, 2025 / Accepted Date: May 29, 2025 / Published Date: May 29, 2025
Abstract
This review explores the critical intersection of immunometabolism and immune cell function. It details how metabolic pathways
like glycolysis and oxidative phosphorylation fuel immune responses, influencing T cell differentiation and macrophage polarization.
The role of mitochondria in immune cell activation and the impact of gut microbiome metabolites on immune homeostasis are
discussed. Furthermore, the abstract covers metabolic reprogramming in cancer for immune evasion, the regulation of inflammatory
balance by metabolic cues, and the distinct metabolic programs of T cells. Pathogen manipulation of host metabolism, the role of
metabolic enzymes in inflammation, and the importance of autophagy for immune homeostasis are also highlighted. Finally, the
influence of dietary interventions on immunometabolism and disease treatment is addressed.
Citation: Costa DR (2026) Immunometabolism: Fueling Immune Responses and Health. Immunol Curr Res 09: 263. Doi: 10.4172/icr.1000263
Copyright: © 2026 Dr. Rafael Costa This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution and reproduction in any medium, provided the original author and source are credited.
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