中国P站

Abstract

Mucosal tissues are essential for immune defense, yet their dysfunction can contribute to the development of autoimmune diseases. Inflammatory processes within mucosal surfaces, such as the gastrointestinal, respiratory, and urogenital tracts, are critical to understanding the pathogenesis of various autoimmune conditions. Dysregulation of immune responses at these sites can lead to chronic inflammation, tissue damage, and autoimmunity. This review examines the immunopathology of mucosal tissues, focusing on the inflammatory mechanisms that underlie autoimmune diseases such as inflammatory bowel disease (IBD), asthma, and systemic lupus erythematosus (SLE). The interaction between the mucosal immune system, microbiota, and environmental factors plays a pivotal role in shaping the immune response. Understanding the molecular pathways involved in mucosal inflammation offers insights into therapeutic targets and potential interventions for autoimmune diseases.