Immunosuppression Strategies: Combating Rejection and Improving Outcomes
Received Date: Jan 02, 2025 / Published Date: Jan 30, 2025
Abstract
This compilation examines current strategies and future directions in immunosuppressive therapy for solid organ transplantation. It delves into the mechanisms of T-cell and antibody-mediated rejection, reviews available immunosuppressive agents, and discusses challenges such as drug resistance and long-term complications. Emerging areas like pharmacogenomics and microbiome modulation offer pathways to personalized treatment. Therapeutic drug monitoring is emphasized for optimizing drug levels and minimizing toxicity. The research aims to enhance graft survival and recipient quality of life.
Keywords: Immunosuppression脥戮 Solid Organ Transplantation脥戮 Graft Rejection脥戮 T-Cell Mediated Rejection脥戮 Antibody-Mediated Rejection脥戮 Pharmacogenomics脥戮 Microbiome脥戮 Drug Resistance脥戮 Innate Immunity脥戮 Therapeutic Drug Monitoring
Citation: El-Khoury F (2025) Immunosuppression Strategies: Combating Rejection and Improving Outcomes. J Clin Exp Transplant 10: 270. Doi: 10.4172/2475-7640.1000270
Copyright: © 2025 Fatima El-Khoury This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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