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ISSN: 2475-7640

Journal of Clinical and Experimental Transplantation
Open Access

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  • Perspective Article   
  • JCET,
  • DOI: 10.4172/2475-7640.1000321

Innovations in Experimental Transplantation Models and Technologies

Angela Russo*
Department of Transplant Sciences, University of Catania, Italy
*Corresponding Author : Angela Russo, Department of Transplant Sciences, University of Catania, Italy, Email: a.russo@catania-transplant.it

Received Date: Nov 03, 2025 / Published Date: Nov 28, 2025

Abstract

This compilation details innovations in experimental transplantation research, encompassing advanced preclinical models, xenotransplantation with genetically modified pigs, and the utilization of organoids and 3D bioprinting. It explores the development of immune-competent humanized mouse models, non-invasive monitoring techniques, and the application of artificial intelligence for outcome prediction. Gene editing, computational modeling for compatibility assessment, and strategies for inducing operational tolerance are also presented. The integration of microfluidic perfusion systems for engineered organs further underscores the rapid advancements in the field.

Keywords: Experimental Transplantation Models; Xenotransplantation; Organoids; 3D Bioprinting; Humanized Mouse Models; Noninvasive Monitoring; Artificial Intelligence; Gene Editing; Operational Tolerance; Microfluidic Systems

Citation: Russo A (2025) Innovations in Experimental Transplantation Models and Technologies. J Clin Exp Transplant 10: 321. Doi: 10.4172/2475-7640.1000321

Copyright: © 2025 Angela Russo This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited

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