Integrating Targeted Therapy into the Management of Bone Sarcomas
Received Date: Mar 01, 2025 / Published Date: Mar 31, 2025
Abstract
Bone sarcomas, including osteosarcoma, Ewing sarcoma, and chondrosarcoma, represent a rare but aggressive group of malignancies primarily affecting children, adolescents, and young adults. Despite advances in multimodal treatments involving surgery and chemotherapy, long-term survival for patients with metastatic or recurrent disease remains poor. The emergence of targeted therapies has introduced new possibilities for improving patient outcomes through precision oncology. These therapies aim to disrupt specific molecular pathways implicated in sarcoma growth and progression. This article explores the current landscape of targeted therapy in bone sarcomas, highlights the integration of molecular profiling into clinical practice, and discusses the challenges and future directions in optimizing these therapies as part of a comprehensive management strategy.
Keywords: Targeted therapy; Bone sarcoma; Osteosarcoma; Ewing sarcoma; Chondrosarcoma; Precision medicine; Molecular profiling; Tyrosine kinase inhibitors; Immunotherapy; Orthopedic oncology
Citation: Irises A (2025) Integrating Targeted Therapy into the Management of Bone Sarcomas. J Orthop Oncol 11: 317. Doi: 10.4172/2472-016X.1000317
Copyright: © 2025 Irises A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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