Mechanisms of Pain Modulation: Neural Pathways, Plasticity, Glia
Received Date: Jul 01, 2025 / Published Date: Jul 29, 2025
Abstract
This research synthesizes findings on pain modulation, investigating neural mechanisms, neuroplasticity, glial cell involvement, and receptor systems. It explores cognitive and lifestyle factors like exercise and sleep, alongside therapeutic targets such as the endocannabinoid system and acupuncture. The studies underscore the complexity of pain perception and the development of chronic pain, highlighting potential avenues for improved therapeutic interventions
Keywords: Pain Modulation; Descending Inhibitory Pathways; Neuroplasticity; Glial Cells; Opioid Receptors; Cognitive Modulation; Exercise; Endocannabinoid System; Sleep Deprivation; Insular Cortex
Citation: Al-Rashid DF (2025) Mechanisms of Pain Modulation: Neural Pathways, Plasticity, Glia. J Pain Relief 14: 759. Doi: 10.4172/2167-0846.1000759
Copyright: © 2025 Dr. Fatima Al-Rashid This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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