Metabolic Pathways: Health, Disease, and Therapeutic Targets
*Corresponding Author: Joseph Mwangi, Department of Molecular Physiology Nairobi Bioscience University, Kenya, Email: j.mwangi@demo.keReceived Date: Nov 03, 2025 / Published Date: Dec 01, 2025
Citation: Mwangi J (2025) Metabolic Pathways: Health, Disease, and Therapeutic Targets. cmb 71: 413.DOI: 10.4172/1165-158X.1000413
Copyright: © 2025 Joseph Mwangi This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
This work reviews key aspects of cellular and systemic metabolism in health and disease. It covers mitochondrial dysfunction in metabolic diseases, the influence of the gut microbiome, nutrient sensing pathways, altered cancer cell metabolism (Warburg effect), the role of autophagy, adipose tissue function, metabolic changes in aging, and advanced analytical techniques like metabolic flux analysis. The regulation and dysregulation of fundamental pathways such as glycolysis and lipid metabolism are also discussed, highlighting their implications for various pathologies and potential therapeutic strategies
