MiRNAs: Key Drivers and Biomarkers in Endometrial Cancer
*Corresponding Author: Dr. Ayesha Khan, All India Institute of Medical Sciences, India, Email: ayesha.khan@rediffmail.comReceived Date: Jun 04, 2025 / Published Date: Jun 30, 2025
Citation: Khan DA (2025) MiRNAs: Key Drivers and Biomarkers in Endometrial Cancer. Current Trends Gynecol Oncol 10: 274.
Copyright: 漏 2025 Dr. Ayesha Khan This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
| Peer-reviewed Full Article 
Abstract
MicroRNAs (miRNAs) are crucial regulators in endometrial cancer (EC) development, impacting proliferation, apoptosis, and metastasis. This review synthesizes research on specific miRNAs, identifying tumor suppressors like miR-200c and miR-199a-3p, and oncomiRs such as miR-181a and miR-21. The study also explores the miR-30 family, miR-99a’s role in the mTOR pathway, circulating miRNAs as biomarkers, inflammation-associated miRNAs, and exosomal miRNAs in the tumor microenvironment. Understanding these miRNA networks is vital for EC diagnostics and therapeutics
