MiRNAs: Key Regulators in Endometrial Cancer Biology
Received Date: Dec 01, 2025 / Published Date: Dec 29, 2025
Abstract
MicroRNAs (miRNAs) are pivotal in endometrial cancer (EC) development, impacting key cellular processes and disease progression. This review synthesizes current understanding of miRNA roles, including their functions as tumor suppressors or oncogenes, their utility in diagnostics and prognostics, and their modulation by epigenetic mechanisms. Emerging research on circulating miRNAs as biomarkers and the development of miRNA-based therapeutics are highlighted. The complex interplay between miRNAs and the tumor microenvironment, as well as their association with chemoresistance, are also discussed. Functional studies are essential for advancing miRNA-based strategies in EC.
Citation: Lee DC (2025) MiRNAs: Key Regulators in Endometrial Cancer Biology. Current Trends Gynecol Oncol 10: 304.
Copyright: 漏 2025 Dr. Charlotte Lee This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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