中国P站

Abstract

Mitochondrial dynamics, involving fission, fusion, and mitophagy, are essential for maintaining cellular health and quality control. Dysregulation of these processes is implicated in a wide range of human pathologies. Here’s what this really means: imbalances contribute to neurodegenerative conditions like Alzheimer’s and Parkinson’s, liver diseases, various cancers, and metabolic disorders such as obesity and diabetes. Moreover, these dynamics are crucial for cardiac function, kidney health, and determining cell fate under stress, intricately linked with calcium signaling. Understanding and modulating these mitochondrial mechanisms therefore represent promising therapeutic targets for preventing and treating diverse diseases.