中国P站

Abstract

Molecular pharmacokinetics is a branch of pharmacology that investigates the fate of drugs within the human body. Understanding how drugs are absorbed, distributed, metabolized, and excreted (ADME) is essential for predicting drug behavior and efficacy. This field integrates molecular biology, biochemistry, and physiology to study the processes that govern drug interactions at the cellular and molecular levels. By examining the mechanistic pathways of drug transport, enzymatic conversion, and elimination, molecular pharmacokinetics provides insights into drug efficacy, toxicity, and potential drug-drug interactions. Advanced techniques in molecular imaging, genetic profiling, and computational modeling are increasingly being applied to enhance drug development, optimize therapeutic strategies, and personalize medicine. This review highlights the key mechanisms involved in drug ADME processes and explores their implications for drug design, clinical applications, and future pharmacological research

Keywords: Molecular pharmacokinetics; Drug absorption; Drug distribution; Drug metabolism; ADME processes; Drug transporters; Enzyme kinetics; Personalized medicine