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ISSN: 2475-7640

Journal of Clinical and Experimental Transplantation
Open Access

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  • Editorial   
  • JCET,
  • DOI: 10.4172/2475-7640.1000267

Monitoring Renal Transplant Rejection: Non-Invasive Advances

Ramesh Iyer*
Department of Organ Transplantation, Chennai Institute of Medical Sciences, India
*Corresponding Author : Ramesh Iyer, Department of Organ Transplantation, Chennai Institute of Medical Sciences, India, Email: r.iyer@chennaitransplant.in

Received Date: Jan 02, 2025 / Published Date: Jan 30, 2025

Abstract

This research synthesizes findings on kidney transplant rejection monitoring, emphasizing non-invasive biomarkers like ddcfDNA and GEP for early detection and personalized treatment. It reviews antibody-mediated rejection (AMR), chronic active AMR, and diagnostic tools including AI in pathology and DSA monitoring. Urinary biomarkers and miRNAs are explored for their non-invasive potential. The data suggests that advanced non-invasive methods complement traditional biopsies, improving graft surveillance and management

Keywords: Renal Transplant Rejection; Non-Invasive Monitoring; Donor- Derived Cell-Free DNA; Gene Expression Profiling; Antibody- Mediated Rejection; Donor-Specific Antibodies; Urinary Biomarkers; MicroRNAs; Artificial Intelligence

Citation: Iyer R (2025) Monitoring Renal Transplant Rejection: Non-Invasive Advances. J Clin Exp Transplant 10: 267 Doi: 10.4172/2475-7640.1000267

Copyright: © 2025 Ramesh Iyer This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited

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