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Abstract

Bone tumors encompass a diverse array of neoplastic conditions that originate in or spread to the skeletal system. These tumors are broadly classified into primary bone tumors, which arise directly from bone tissue, and secondary (metastatic) bone tumors, which are more common and result from the spread of malignancies from other parts of the body. Understanding the biological behavior, clinical manifestations, diagnostic pathways, and therapeutic strategies for both primary and secondary bone tumors is critical in optimizing patient outcomes. This article provides an in-depth analysis of the differences and similarities between these tumor types, explores the evolving diagnostic tools and treatment modalities, and emphasizes the importance of a multidisciplinary approach in managing the spectrum of bone neoplasms.