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Neonatal and Pediatric Medicine
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  • Neonat Pediatr Med 2025, Vol 11(12): 12

Neonatal Gut Microbiota: Development, Influences, and Therapeutics

Dr. Mei Ling Chen*
Dept. of Microbiology, Singapore Pediatric Health Sciences, Singapore
*Corresponding Author : Dr. Mei Ling Chen, Dept. of Microbiology, Singapore Pediatric Health Sciences, Singapore, Email: mei.chen@bioinst.sg

Received Date: Dec 05, 2025 / Published Date: Jan 02, 2026

Abstract

The neonatal gut microbiota plays a critical role in infant development, influencing immune maturation, nutrient metabolism,
and protection against pathogens. Factors such as delivery mode, feeding practices, and antibiotic exposure significantly shape its
composition. Early colonization patterns, the impact of human milk oligosaccharides, and the connection to the immune system
and gut-brain axis are key areas of research. Disruptions in the microbiome can lead to adverse health outcomes like allergies and
necrotizing enterocolitis. Probiotics and fecal microbiota transplantation are being explored as therapeutic interventions, highlighting
the ongoing importance of understanding and modulating the neonatal gut microbiome for long-term health.

Citation: Chen DML (2026) Neonatal Gut Microbiota: Development, Influences, and Therapeutics. NNP 11: 608.

Copyright: 漏 2026 Dr. Mei Ling Chen This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permitsunrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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