Neonatal HIE: Hypothermia, Imaging, and Future Therapies
Received Date: Nov 01, 2025 / Published Date: Nov 30, 2025
Abstract
Neonatal hypoxic-ischemic encephalopathy (HIE) is a critical condition leading to brain injury from oxygen deprivation. Thera
peutic hypothermia is a standard treatment that improves outcomes. Advanced neuroimaging and biomarkers aid in early diagnosis
and prognosis. Ongoing research focuses on novel neuroprotective strategies, including pharmacological agents and stem cell thera
pies. The effectiveness of hypothermia in reducing mortality and disability is well-established, with current efforts aimed at optimiz
ing its application and exploring adjunct treatments. Neuroimaging and biomarkers play crucial roles in assessment and prediction,
while understanding HIE’s complex pathophysiology informs therapeutic development. Stem cell therapy and pharmacological ad
juncts represent promising future directions for mitigating brain damage and promoting recovery.
Citation: 脗聽Ivanova O (2025) Neonatal HIE: Hypothermia, Imaging, and Future Therapies. NNP 11: 602.
Copyright: 聽漏 2025 Olga Ivanova This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution and reproduction in any medium, provided the original author and source are credited.
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