Neonatal Immunity: Development, Vulnerabilities, and Future Vaccines
Received Date: Sep 01, 2025 / Accepted Date: Sep 29, 2025 / Published Date: Sep 29, 2025
Abstract
The neonatal immune system is a complex and evolving entity characterized by unique innate and adaptive responses shaped by
maternal contributions and early environmental exposures. Vulnerability to infection stems from immature immune cell functions,
skewedThelpercellpolarization, and developing complement pathways. Maternal antibodies offer essential passive immunity, while
the gut microbiome plays a critical role in immune maturation and tolerance. Challenges in neonatal vaccination arise from immune
hyporesponsiveness, prompting research into novel strategies. Understanding these developmental aspects is key to safeguarding
infant health and improving vaccine efficacy
Keywords:
Citation: Al-Farsi DN (2025) Neonatal Immunity: Development, Vulnerabilities, and Future Vaccines. Immunol Curr Res 09: 276. Doi: 10.4172/icr.1000276
Copyright: © 2025 Dr. Noor Al-Farsi This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution and reproduction in any medium, provided the original author and source are credited.
Select your language of interest to view the total content in your interested language
Share This Article
Recommended Journals
Open Access Journals
Article Tools
Article Usage
- Total views: 171
- [From(publication date): 0-0 - Apr 23, 2026]
- Breakdown by view type
- HTML page views: 131
- PDF downloads: 40
