Neonatal Sepsis: Diagnosis, Treatment, and Outcomes
*Corresponding Author:Received Date: Dec 01, 2025 / Published Date: Dec 29, 2025
Citation: Verma P (2025) Neonatal Sepsis: Diagnosis, Treatment, and Outcomes. jpms 09: 361.DOI: 10.4172/jpms.1000361
Copyright: © 2025 Pooja Verma This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Neonatal sepsis is a critical challenge demanding immediate attention. This compilation reviews its pathogenesis, diagnosis, and management, emphasizing early antibiotic therapy and novel biomarkers. Molecular mechanisms, immune dysregulation, and the gut microbiome are explored. Diagnostic tools and the impact of antimicrobial resistance are discussed, alongside antibiotic stewardship principles. Long-term neurodevelopmental outcomes and specific management in congenital heart disease are highlighted. Adjunctive therapies and evidence-based guidelines are also examined, with research identifying mortality risk factors.
