Neuropathic Pain: Mechanisms, Targets, and Hope
Received Date: May 01, 2025 / Published Date: May 29, 2025
Abstract
Neuropathic pain, a complex condition arising from nervous system damage, is characterized by neuroinflammation, ion channel dysregulation, and glial activation. Current research explores novel therapeutic targets that address underlying mechanisms beyond symptomatic relief. Insights into immune system involvement, central sensitization, and genetic factors are advancing treatment strategies. Limitations of existing pharmacotherapies necessitate a focus on regenerative medicine and cell-based therapies for nerve repair. Addressing the psychosocial impact and diagnostic challenges are vital for holistic patient care.
Keywords: Neuropathic Pain脥戮 Neuroinflammation脥戮 Ion Channels脥戮 Glial Cells脥戮 Therapeutic Targets脥戮 Central Sensitization脥戮 Regenerative Medicine脥戮 Pharmacotherapy脥戮 Psychosocial Impact脥戮 Nerve Damage
Citation: Alvarez SM (2025) Neuropathic Pain: Mechanisms, Targets, and Hope. J Pain Relief 14: 735. Doi: 10.4172/2167-0846.1000735
Copyright: © 2025 Sofia M. Alvarez This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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