Non-coding RNAs: Regulators, Biomarkers, and Therapeutic Targets
*Corresponding Author: Minh Tran, Department of Molecular Genomics Saigon Institute of Biotechnology, Vietnam, Email: m.tran@sample.vnReceived Date: Nov 03, 2025 / Published Date: Dec 01, 2025
Citation: Tran M (2025) Non-coding RNAs: Regulators, Biomarkers, and Therapeutic Targets. cmb 71: 414.DOI: 10.4172/1165-158X.1000414
Copyright: © 2025 Minh Tran This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Non-coding RNAs (ncRNAs) are pivotal regulators of gene expression in health and disease. This compilation explores the multifaceted roles of microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) in cellular processes and pathogenesis, particularly in cancer and neurological disorders. Studies highlight their potential as diagnostic biomarkers and therapeutic targets, with investigations into specific ncRNAs such as LINC01234, circHIPK3, miR-21, HOTAIR, CDR1as, and MALAT1. The immunomodulatory functions of exosomal ncRNAs and the protective role of miR-1 in cardiac hypertrophy are also discussed. Emerging ncRNA classes and technological advancements are shaping the future of ncRNA research and therapeutic interventions.
