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ISSN: 2475-7640

Journal of Clinical and Experimental Transplantation
Open Access

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  • Perspective Article   
  • JCET,
  • DOI: 10.4172/2475-7640.1000282

Novel Biomarkers Advance Transplant Monitoring and Outcomes

Ingrid Svensson*
Department of Transplant Research, Uppsala University, Sweden
*Corresponding Author : Ingrid Svensson, Department of Transplant Research, Uppsala University, Sweden, Email: i.svensson@uppsalatransplant.se

Received Date: Mar 03, 2025 / Published Date: Mar 31, 2025

Abstract

Recent research focuses on novel biomarkers for enhancing transplant outcomes. Studies investigate urinary microRNAs and donor-derived cell-free DNA for early detection of kidney allograft injury and rejection. Other work explores circulating microRNAs for heart transplant rejection, gene expression profiling for liver transplant monitoring, and donor-specific antibodies for kidney transplant survival. Additionally, chemokines, cytokine panels, exosomal proteins, and cfDNA methylation patterns are examined for various rejection types and immune monitoring across different transplant types, aiming for non-invasive and early diagnostic tools to improve graft survival.

Keywords: Biomarkers; Transplant; Rejection; Non-invasive Monitoring; Early Detection; MicroRNAs; Cell-Free DNA; Cytokines; Gene Expression; Allograft Survival

Citation: Svensson I (2025) Novel Biomarkers Advance Transplant Monitoring and Outcomes. J Clin Exp Transplant 10: 282 Doi: 10.4172/2475-7640.1000282

Copyright: © 2025 Ingrid Svensson This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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