Obesity: Multifaceted Mechanisms, Systemic Crosstalk
Received Date: Nov 01, 2025 / Published Date: Dec 01, 2025
Abstract
Obesity is a complex metabolic disease influenced by diverse biological factors. Research highlights the critical roles of adipose tissue crosstalk, gut microbiota alterations, and inflammatory processes in the brain and fat tissue. Epigenetic modifications, mitochondrial dysfunction, and intercellular communication via exosomes also contribute to systemic metabolic dysfunction. Collectively, these studies identify a wide range of molecular mechanisms and potential therapeutic targets for obesity, emphasizing its multifaceted nature and the interconnectedness of various physiological systems in its pathogenesis
Citation: Perez SD (2025) Obesity: Multifaceted Mechanisms, Systemic Crosstalk. jowt 15: 864.
Copyright: 漏 2025 Samuel D. Perez This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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