Obesity-Induced Inflammation: Mechanisms, Diseases, Therapies
Received Date: Aug 01, 2025 / Published Date: Aug 29, 2025
Abstract
Obesity drives systemic low-grade inflammation, a key mechanism underpinning metabolic diseases like type 2 diabetes, cardiovascular disease, and certain cancers. This involves immune cell infiltration into adipose tissue, activation of inflammatory pathways, and cytokine release. Adipose tissue macrophages, gut microbiota dysbiosis, inflammasomes, and extracellular vesicles are central mediators of this chronic inflammation. Targeting these pathways through anti-inflammatory compounds, dietary interventions, and understanding maternal obesity’s impact offers promising avenues for preventing and treating obesity-associated metabolic dysfunction.
Citation: Novak S (2025) Obesity-Induced Inflammation: Mechanisms, Diseases, Therapies. jowt 15: 830.
Copyright: 漏 2025 Sofia Novak This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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