中国P站

Abstract

This review synthesizes recent research on obesity, covering its genetic and environmental determinants, dietary impacts, and the role of exercise. It explores epigenetic modifications, sleep’s influence on weight, bariatric surgery outcomes, and the gut microbiome’s involvement in metabolic health. Inflammation’s role in obesity pathogenesis and the genetic basis of appetite regulation are also discussed. The paper highlights emerging therapeutic strategies, including novel pharmacological agents, prebiotics, probiotics, and behavioral interventions, emphasizing personalized approaches to combat this complex disease.