Optimizing Donor Matching: Protocols for Transplantation Success
Received Date: May 01, 2025 / Published Date: May 29, 2025
Abstract
This compilation highlights the critical role of refined clinical protocols in advancing donor matching for organ and stem cell transplantation. It emphasizes strategies for managing complex scenarios like ABO-incompatible and HLA-mismatched recipients, as well as highly sensitized patients. The integration of immunogenetics, desensitization therapies, advanced HLA typing, and monitoring for donor-specific antibodies are presented as key to improving graft survival and patient outcomes across kidney, liver, lung, heart, and hematopoietic stem cell transplantation.
Keywords: Donor Matching脥戮 Transplantation Protocols脥戮 Immunological Risk脥戮 Graft Survival脥戮 ABO Incompatibility脥戮 HLA Matching脥戮 Highly Sensitized Recipients脥戮 Desensitization Therapy脥戮 Antibody-Mediated Rejection脥戮 Next-Generation Sequencing
Citation: Pereira S (2025) Optimizing Donor Matching: Protocols for Transplantation Success. J Clin Exp Transplant 10: 292 Doi: 10.4172/2475-7640.1000292
Copyright: © 2025 Sofia Pereira This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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