Optimizing Immunosuppression for Solid Organ Transplant Longevity
Received Date: Jul 02, 2025 / Published Date: Jul 30, 2025
Abstract
This review consolidates recent research on immunosuppression strategies for solid organ transplantation, aiming to enhance graft longevity. It highlights personalized approaches, the role of the microbiome and regulatory T cells, and advancements in managing antibody-mediated rejection. Strategies for minimizing drug toxicity and addressing specific transplant types and patient populations, such as the elderly, are examined. The overarching goal is to improve long-term graft survival and patient outcomes through refined immunosuppressive protocols
Keywords: Immunosuppression脥戮 Solid Organ Transplantation脥戮 Graft Longevity脥戮 Personalized Immunosuppression脥戮 Microbiome Modulation脥戮 Regulatory T Cells脥戮 Antibody-Mediated Rejection脥戮 Calcineurin Inhibitors脥戮 Belatacept脥戮 Cardiac Allograft Vasculopathy
Citation: Sato Y (2025) Optimizing Immunosuppression for Solid Organ Transplant Longevity. J Clin Exp Transplant 10: 294. Doi: 10.4172/2475-7640.1000294
Copyright: © 2025 Yuki Sato This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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