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Abstract

Solid organ transplantation success hinges on optimizing immunosuppressive protocols to ensure graft survival while minimizing patient risks like infection and malignancy. Personalized approaches, risk stratification, and novel therapies are advancing care. Key challenges include infection prevention, managing PTLD, addressing cardiovascular complications, and mitigating drug toxicity, particularly in vulnerable populations like the elderly. Emerging strategies involve pharmacogenomics and novel immunosuppressants, underscored by the critical role of immune monitoring for tailored, safe, and effective immunosuppression

Keywords: Immunosuppression脥戮 Graft Survival脥戮 Patient Safety脥戮 Infection Prevention脥戮 PTLD脥戮 Cardiovascular Complications脥戮 Personalized Medicine脥戮 Pharmacogenomics脥戮 Transplant Recipients脥戮 Novel Immunosuppressants