Optimizing Solid Organ Transplant Management: Biomarkers and Immunosuppression
Received Date: May 01, 2025 / Published Date: May 29, 2025
Abstract
Monitoring solid organ transplant recipients involves navigating the complexities of graft rejection and drug toxicity. This overview highlights the shift towards non-invasive biomarkers and personalized immunosuppression, addressing challenges in differentiating rejection from drug-induced injury. Research into genetic factors, drug mechanisms, viral influences, and novel detection methods like cell-free DNA and microRNAs are crucial for early intervention and improved outcomes. Management strategies for specific toxicities and complications like PTLD are also discussed
Keywords: Transplant Rejection脥戮 Drug Toxicity脥戮 Immunosuppression脥戮 Noninvasive Monitoring脥戮 Donor-Derived Cell-Free DNA脥戮 Exosomal MicroRNAs脥戮 Calcineurin Inhibitors脥戮 mTOR Inhibitors脥戮 Viral Infections脥戮 Highly Sensitized Patients
Citation: Rossi D (2025) Optimizing Solid Organ Transplant Management: Biomarkers and Immunosuppression. J Clin Exp Transplant 10: 284 Doi: 10.4172/2475-7640.1000284
Copyright: © 2025 Daniela Rossi This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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