Pain and Sleep: A Bidirectional Exacerbating Relationship
Received Date: Jul 01, 2025 / Published Date: Jul 29, 2025
Abstract
Chronic pain and sleep disturbances exhibit a profound bidirectional relationship, creating a cycle that impacts patient well-being and treatment outcomes. This review explores the interplay, including insomnia as a comorbidity managed with CBT-I, the role of sleep apnea, and neurobiological links. Fibromyalgia and neuropathic pain highlight significant sleep impairments. Circadian rhythm disruption and inflammatory processes are also implicated. Opioid therapy can cause adverse sleep effects. A holistic approach addressing both pain and sleep is crucial for comprehensive care and improved patient function.
Keywords: Chronic Pain脥戮 Sleep Disturbances脥戮 Insomnia脥戮 CBT-I脥戮 Sleep Apnea脥戮 Neurobiological Mechanisms脥戮 Fibromyalgia脥戮 Circadian Rhythm脥戮 Opioid Therapy脥戮 Inflammation
Citation: O’Connell DP (2025) Pain and Sleep: A Bidirectional Exacerbating Relationship. J Pain Relief 14: 760 Doi: 10.4172/2167-0846.1000760
Copyright: 2025 Dr. Peter O’Connell This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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