Pain Pathways: Molecular to Chronic Relief
Received Date: Jun 02, 2025 / Published Date: Jun 30, 2025
Abstract
Pain signaling involves complex neural pathways initiated by nociceptors and processed in the central nervous system. Glial cells, ion channels, and neurotransmitters critically regulate pain transmission. Central sensitization amplifies pain signaling, contributing to chronic pain states, which are further influenced by molecular changes and emotional factors. Therapeutic approaches target these mechanisms to alleviate pain, facing challenges in achieving selectivity and efficacy.
Keywords: Pain Pathways脥戮 Nociception脥戮 Glial Cells脥戮 Ion Channels脥戮 Central Sensitization脥戮 Neurotransmitters脥戮 Chronic Pain脥戮 Pain Modulation脥戮 Epigenetics脥戮 Pain Perception
Citation: Dubois C (2025) Pain Pathways: Molecular to Chronic Relief. J Pain Relief 14: 745. Doi: 10.4172/2167-0846.1000745
Copyright: © 2025 Claire Dubois This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
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