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Journal of Dental Pathology and Medicine
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  • Opinion Article   
  • J Dent Pathol Med,
  • DOI: 10.4172/jdpm.1000281

Periodontal Disease: Microbial, Immune, and Systemic Links

Dr. Ahmed Hassan*
Department of Periodontology, Cairo Dental University, Egypt
*Corresponding Author : Dr. Ahmed Hassan, Department of Periodontology, Cairo Dental University, Egypt, Email: ahassan@cdu.edu.eg

Received Date: Jun 02, 2025 / Accepted Date: Jun 30, 2025 / Published Date: Jun 30, 2025

Abstract

Periodontal disease is a multifaceted global health challenge influenced by microbial dysbiosis, host immune responses, and sys
temic conditions. Emerging research highlights the gut-oral axis, inflammatory pathways, and genetic factors in disease pathogenesis.
Therapeutic strategies are evolving to include targeted antimicrobial and immunomodulatory agents, microbiome modulation, and
advancedregenerative techniques. Diagnostic tools are improving with molecular and salivary biomarkers, while antibiotic resistance
necessitates careful management. The impact on quality of life underscores the need for comprehensive care.

Citation: Hassan DA (2025) Periodontal Disease: Microbial, Immune, and Systemic Links. J Dent Pathol Med 09: 281. Doi: 10.4172/jdpm.1000281

Copyright: © 2025 Dr. Ahmed Hassan This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permitsunrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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